BuyseTest: Generalized Pairwise Comparisons

Implementation of the Generalized Pairwise Comparisons (GPC) as defined in Buyse (2010) <doi:10.1002/sim.3923> for complete observations, and extended in Peron (2018) <doi:10.1177/0962280216658320> to deal with right-censoring. GPC compare two groups of observations (intervention vs. control group) regarding several prioritized endpoints to estimate the probability that a random observation drawn from one group performs better/worse/equivalently than a random observation drawn from the other group. Summary statistics such as the net treatment benefit, win ratio, or win odds are then deduced from these probabilities. Confidence intervals and p-values are obtained based on asymptotic results (Ozenne 2021 <doi:10.1177/09622802211037067>), non-parametric bootstrap, or permutations. The software enables the use of thresholds of minimal importance difference, stratification, non-prioritized endpoints (O Brien test), and can handle right-censoring and competing-risks.

Version: 3.0.5
Depends: R (≥ 2.10), Rcpp
Imports: data.table, doSNOW, foreach, ggplot2, methods, lava, parallel, prodlim, riskRegression, rlang, scales, stats, stats4, utils
LinkingTo: Rcpp, RcppArmadillo
Suggests: cvAUC, mvtnorm, pbapply, pROC, R.rsp, survival, testthat
Published: 2024-10-13
DOI: 10.32614/CRAN.package.BuyseTest
Author: Brice Ozenne ORCID iD [aut, cre], Eva Cantagallo [aut], William Anderson [aut], Julien Peron [ctb], Johan Verbeeck [ctb]
Maintainer: Brice Ozenne <brice.mh.ozenne at gmail.com>
BugReports: https://github.com/bozenne/BuyseTest/issues
License: GPL-3
URL: https://github.com/bozenne/BuyseTest
NeedsCompilation: yes
Citation: BuyseTest citation info
Materials: NEWS
In views: CausalInference
CRAN checks: BuyseTest results

Documentation:

Reference manual: BuyseTest.pdf
Vignettes: BuyseTest: overview (source)
BuyseTest: wilcoxon test (source)

Downloads:

Package source: BuyseTest_3.0.5.tar.gz
Windows binaries: r-devel: BuyseTest_3.0.5.zip, r-release: BuyseTest_3.0.5.zip, r-oldrel: BuyseTest_3.0.5.zip
macOS binaries: r-release (arm64): BuyseTest_3.0.5.tgz, r-oldrel (arm64): BuyseTest_3.0.5.tgz, r-release (x86_64): BuyseTest_3.0.5.tgz, r-oldrel (x86_64): BuyseTest_3.0.5.tgz
Old sources: BuyseTest archive

Linking:

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