graposas: Graphical Approach Optimal Sample Size
Graphical approach provides a useful framework for multiplicity adjustment in clinical trials with multiple endpoints. This package includes statistical methods to optimize sample size over initial weight and transition probability in a graphical approach under a common setting, which is to use marginal power for each endpoint in a trial design.
See Zhang, F. and Gou, J. (2023). Sample size optimization for clinical trials using graphical approaches for multiplicity adjustment, Technical Report.
Version: |
1.0.0 |
Depends: |
R (≥ 4.2.0) |
Imports: |
GA (≥ 3.0.0), graphics (≥ 4.2.0), mvtnorm (≥ 1.1.0), stats (≥ 4.0.0) |
Published: |
2023-08-17 |
DOI: |
10.32614/CRAN.package.graposas |
Author: |
Jiangtao Gou [aut, cre],
Fengqing (Zoe) Zhang [aut] |
Maintainer: |
Jiangtao Gou <gouRpackage at gmail.com> |
License: |
GPL-3 |
NeedsCompilation: |
no |
CRAN checks: |
graposas results |
Documentation:
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