rpedgene (pedgene on CRAN)
Gene-level kernel and burden association tests of genetic variants with a trait of interest, allowing for related individuals, including twins.
Authors
Daniel J. Schaid and Jason P. Sinnwell Small contribution by A. Visconti
Manuscript:
Schaid DJ, McDonnell SK., Sinnwell JP, Thibodeau SN. (2013) Multiple Genetic Variant Association Testing by Collapsing and Kernel Methods With Pedigree or Population Structured Data Genet Epidemiol, 37(5):409-18